pentobarbital will lessen the level or impact of parecoxib by influencing hepatic enzyme CYP2C9/ten metabolism. Use Caution/Check.pentobarbital will lower the extent or result of cevimeline by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Not known.pentobarbital will decrease the extent or result of ixabepilone b